Modular nature of simian foamy virus genomes and their evolutionary history
نویسندگان
چکیده
منابع مشابه
Molecular Ecology and Natural History of Simian Foamy Virus Infection in Wild-Living Chimpanzees
Identifying microbial pathogens with zoonotic potential in wild-living primates can be important to human health, as evidenced by human immunodeficiency viruses types 1 and 2 (HIV-1 and HIV-2) and Ebola virus. Simian foamy viruses (SFVs) are ancient retroviruses that infect Old and New World monkeys and apes. Although not known to cause disease, these viruses are of public health interest becau...
متن کاملCharacterization of provirus clones of simian foamy virus type 1.
We have cloned proviral DNA of simian foamy virus type 1 (SFV-1) from linear unintegrated DNA (pSFV-1). Transfection of pSFV-1 induces cytopathology in several cell lines with supernatants from the transfected cell culture containing infectious viral particles. Electron microscopy of the transfected cells revealed foamy virus particles. Deletion analysis of pSFV-1 indicated that the transcripti...
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The structure of foamy virus, its mode of maturation, and the origin of vacuoles in monkey kidney cells are described.
متن کاملSimian foamy virus isolated from an accidentally infected human individual.
Evidence for natural foamy virus (FV) infections in humans is still lacking. However, accidental infections of humans with simian FV have been demonstrated by serology and PCR, but all previous attempts to recover infectious virus in such cases have failed. Here we describe the isolation of a simian FV from peripheral blood mononuclear cells (PBMC) of a healthy animal caretaker, who acquired th...
متن کاملAntigenic relationship of human foamy virus to the simian foamy viruses.
A foamy virus isolated by Achong et al. from a human nasopharyngeal carcinoma was studied to determine its antigenic relationship to the eight known simiam foamy viruses (SFV). Using reciprocal cross-immunofluorescent and cross-neutralization techniques, we found the human isolate to be closely related to SFV type 6. In a seroepidemiological survey, neutralizing antibody to the human foamy viru...
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ژورنال
عنوان ژورنال: Virus Evolution
سال: 2019
ISSN: 2057-1577
DOI: 10.1093/ve/vez032